Ko te wā takawhīwhiwhi i tapa e te tākuta Humphrey Osmond nei aroaro reira ki Te New York Academy o Sciences i 1957. Kei te ahu mai te reira i te kupu kariki psyche, e te tikanga wairua hinengaro ranei, a ka muku i te tikanga 'ki te faaite mai'.
He rerekē momo o matū takawhīwhiwhi. Ētahi tupu noatia i roto i te tipu pērā i te harore me te cacti. E synthesized ētahi atu, ka tukua i roto i te papa, pepa blotter, puehu me te ake.
Kua Psychedelics whakamahia hoki mano o nga tau e ngā ahurea huri noa i te ao mo ratou pānga pūngāwerewere me te wairua. Kua ēnei matū ako e pūtaiao, kaihaumanu me toi mai i te 1930, me kua mai kua rāhuitia i raro i te Tairururaa United Nations I Runga I Matū Psychotropic, a riro te moni anō kua e kuate tipu mai i te 1970.
