He aha te anandamide?
He matū e kiia ana ko te kupu "ngota ngota koa" na te mea ko tona ingoa, ko ananda, i ahu mai i Te Sanskrit, ko te tikanga he koa, he koa ranei. Ko tona ingoa matū tonu ko: N-arachidonoylethanolamine. No te roopu o nga matū i roto i te tinana e kiia ana ko te waikawa momona amides, he waahanga o te tinana o te tangata ake (endo, te tikanga "roto") te punaha cannabinoid. He rereke ki te cannabinoids exogenous
(ko te tikanga o te kupu "i waho") pēnei i TE THC, cbd etc. e pau.
Ko te mea pono, ko te hanganga matū o te anandamide he rite tonu ki TE thc. Tata taea e tetahi te mea i whanaunga ratou, ki THC rite te exogenous cannabinoid waho, me te anandamide rite te ā - "endogenous"kotahi.
Ka taunekeneke a Anandamide me nga kaiwhakawhiwhi CB2 me CB1; ko te tikanga ka pangia e ia tetahi mea i roto i te roro me te punaha o te pokapū pokapū. Ka rite ki te THC, he cannabinoid e puta ai te ahua motuhake o te "tiketike", me te whakanui ake i te hiahia me te momoe me te waatea. Reira nui hoki te wāhi nui i roto i te maha atu mahi faufaa i roto i te tinana tangata.
Cannabinoids me te roro
I nga tau 1960 Ko Raphael Mechoulam, he kaiputaiao me te kaiputaiao no Iharaira, te cannabinoids tuatahi i wehe. I te tīmatanga whakatau i te hanganga matū o MÄKAURAU, i taea e ki te tutakina THC RITE te TE pūhui psychoactive matua kitea i roto i tarukino ia me tona rōpū rangahau.
Tenei, o te akoranga, arahina kistudies i runga i TE pānga o THC i runga i te hinengaro me te tinana, me te ko reira te mutunga te pūtaiao take inaianei mohio o te pūnaha endocannabinoid. Whai muri i te mahi nui A Mechoulam i te mara o te endocannabinoids, i whakatau nga kaiputaiao ka kitea tetahi mea penei i te kaiwhiwhi cannabinoid i tetahi waahi i roto i te roro, i te tinana ranei. Na Tenei I puta ai Te kaiputaiao A Allyn Howlett, me tana roopu I Te Whare Wananga o St. Louis, ki te rapu taunakitanga tuturu kei roto i te tinana o te tangata ona ake kaiwhakawhiwhi cannabinoid, a KO TE THC E uru tika ana ki enei kaiwhakawhiwhi. Na tenei kitenga i puta ai te patai he aha te take ka whiwhi te tinana i tetahi kaiwhiwhi cannabinoid (e pai ana KI TE THC tata ki roto) mena kaore te THC E puta i roto i te tinana ake. Ko te pātai i fehangahangai pūtaiao ki a te ahai te mutunga ka arahina ki te kitea o te anandamide.
Ko te tinana i whakaputa i tana ake cannabinoid taiao i tino kitea e Te roopu A Raphael Mechoulam i a raatau e whakahaere ana i a raatau rangahau tuatahi. Heoi, kaore i tae noa ki te 1992 e rua o taua roopu rangahau taketake - Ko William Devane me Lumir Hanus - i kitea te waahanga whakamutunga o te panga, i tapaina e ratou ko anandamide (i whakaaweahia, pera i whakahuatia i mua, na te kupu Sanskrit mo bliss: "Ananda"). Ahakoa TE PAI o TE THC KI te kaiwhiwhi cannabinoid o te tinana, ka tino uru te anandamide ki roto.
Ko te kitenga o te anandamide kua tino whai waahi ki te maarama o te putaiao ki te tarukino me te tinana o te tangata. Te wehe me te ite i te endocannabinoidkua whakapumautia e reira he, i roto i te meka, he pūnaha completeocannabinoid oti i roto i te tinana. Ko te mau farii ohipa cannabinoid me fakanatula hua cannabinoids whakaatu e reira ko te pūnaha oti o cannabinoids, i waho te hiahia mo te tarukino, e mahi i roto i te roro tangata, me te tinana.
He aha te mahi a anandamide?
He maha tonu nga mea e kitea ana mo te huarahi e mahi ai te anandamide i roto i te tinana. I muri i te katoa, ko reira wahi o tetahi o nga pūnaha tino matatini i roto ia tatou. Ka taea e ia te whakakore i te ahua o te hari ake i te maha o nga kaiwhakamahi cannabis ka tutuki i muri i te paowa, i te kai ranei. I tua atu, anandamide hoki mahi i roto i aua wahi o te roro e pā i te sensations o te mamae, mahara, hiahia, kaupapa, me te ara taua āhuatanga ritehihiri.
Reira pānga hoki te pūnaha whakaputa uri, me te, ko te kupu, hua. Ka rite ki te neurotransmitter, kei te pakaru te reira iho hohoro i roto i te tinana, i te mea he aha e kore he roa tonu te pānga faateiteiraa. Ko te Anandamide te whakanui ake i te neurogenesis - te hanganga o nga neurons hou, nga hononga neural hou ranei. Na tenei ahuatanga ahurei, ka kii nga kairangataiao ka taea pea e te anandamide te mahi ki te awangawanga me te pouri. Te mea faahiahia, kei te haere ano hoki te reira i runga i ki whanau hou i roto i te waiu uma o te whaea.
Anandamide, THC me CBD – Me Pehea te Taunekeneke
A, no te ingested tarukino te, te thc pūhui psychoactive tāwhai aha e meatia e anandamide. KO TE rerekētanga ko E ORA THC i roto i te tinana nui roa atu i te anandamide e, rite whakahuatia i runga ake, wawahi ihotino hohoro.
Mo te hunga e whakaputa ana i te anandamide iti, ko te taapiri O TE THC me tona whakaongaonga o te kaiwhiwhi cannabinoid ka taea te waihanga i te paanga tino mai.
Ko te TIKANGA, ka taunekeneke te CBD me te tinana o te tangata i roto i tetahi ahuatanga rereke, kaore he painga hinengaro; engari, he mea whakaongaonga ki te mahi taiao o te punaha endocannabinoid.
Ārai te reira i te hanga o FAAH, i te mea he whākōkī i roto i te tinana e wawahi iho anandamide. Ko te tikanga tenei ka roa ake te ora o te anandamide ka uru ana TE CBD ki te tinana. Reira whakaongaonga hoki te tinana ki te whakaputa i atu o reira. Hangaia e te mana'o o te nui haere te oranga, me te oaoa tenei, me te he whakaiti i roto i te mumura me te mamae.
Ētahi pūtaiao ii whakaarohia ko te anandamide ka puta noa i roto i te tinana i te wa e noho ana te tangata i te ahua o te whakangahau hohonu, te kukume whakarei ake ranei: hei tauira, i te wa e hanga ana, e whakarongo ana ranei ki te puoro, kanikani, tuhi auaha, aha atu. fele, tetahi whakakoro e heightens arotahi whakangā ranei. Ko te kupu, tenei endocannabinoid ngaro kia tākaro i te wahi i roto i te aha tarukino he pera hurinoa pārekareka ki na maha, ahakoa o te tau, ira, papamuri ranei.
Ko te hinengaro hinengaro i te rautau 20-ko te waa roha
History o Microdosing
